Medidas antropométricas em idosos assistidos na atenção básica e sua associação com gênero, idade e síndrome da fragilidade: dados do EMI-SUS / Anthropometric measurements in elderly assisted in primary health care and their association with gender, age and frailty syndrome: EMI-SUS data

Objetivos: Descrever medidas antropométricas em idosos assistidos na atenção básica e analisar sua associação com gênero, idade e síndrome da fragilidade. Métodos: Este estudo transversal é parte do Estudo Epidemiológico e Clínico dos Idosos Atendidos pela Estratégia Saúde da Família de Porto Alegre-RS-Brasil (EMI-SUS). Foram obtidas dos idosos 27 medidas antropométricas (analisadas de forma isolada ou em equações, totalizando 41 dados de medidas antropométricas) e dados para determinação da síndrome de fragilidade (Fenótipo de Fried). Foram utilizados o teste de Kolmogorov-Smirnov, o teste t de Student e o teste de análise de variância (ANOVA). Considerou-se o nível de confiança de 95%. Resultados: A amostra incluiu 583 idosos, sendo 371 (63,6%) mulheres. Homens apresentaram médias significativamente superiores de peso, estatura, altura do joelho, circunferências (antebraço, muscular do braço, pescoço, punho), área muscular do braço, relações (cintura/quadril, cintura/coxa, dobras tronco/extremidades) e índices (sagital, de conicidade). Mulheres apresentaram médias superiores do índice de massa corporal, circunferências (braço, cintura, coxa, quadril), dobras cutâneas (bicipital, tricipital, subescapular, suprailíaca, peitoral, coxa, panturrilha, média seis dobras), área de gordura do braço, relação cintura/estatura e relação diâmetro abdominal sagital/estatura. Idosos mais jovens apresentaram medidas superiores das circunferências do antebraço, braço, músculo do braço, coxa e área muscular do braço em relação aos mais velhos. Idosos robustos tinham estatura, altura do joelho, circunferência muscular do braço e área muscular do braço superiores e área de gordura do braço, dobras cutâneas da coxa, peitoral, bicipital, tricipital, panturrilha e relação diâmetro abdominal sagital/estatura inferiores aos frágeis e pré-frágeis. Idosos frágeis tinham circunferências da panturrilha e antebraço menores e relações cintura/estatura, cintura/coxa, cintura/panturrilha e índices de conicidade e sagital, maiores que os robustos. Conclusões: As medidas antropométricas mostraram-se associadas com gênero, idade e fragilidade. Nos homens, as médias das medidas de tamanho, compleição e de reserva de massa muscular foram maiores. Nas mulheres, as médias das medidas de reserva adiposa foram maiores e a associação das medidas com a faixa etária foi mais frequente. Fragilidade mostrou-se associada com perda de massa muscular. Idosos frágeis apresentaram medidas inferiores de tamanho e compleição.

Aims: To describe anthropometric measurements and analyze their association with gender, age, and frailty syndrome in elderly assisted in primary health care. Methods: This cross-sectional study is part of the Multidimensional Study of the Elderly in the Family Health Strategy in Porto Alegre, RS, Brazil (EMI-SUS). Twenty-seven anthropometric measurements (analyzed in isolation or in equations, totaling 41 measurements) and data for determining the frailty (Fried Phenotype) were collected from elderly individuals. Kolmogorov-Smirnov test, Student t test and analysis of variance (ANOVA) were used for statistical analysis, considering a confidence level of 95%. Results: The sample included 583 elderly, of whom 371 (63.6%) were women. Men presented significantly higher means for weight, height, knee-height; forearm, muscle arm, neck and wrist circumferences; muscle arm area; ratios for waist-to-hip, waist-to-thigh, and trunk-to-skinfolds-extremities; and sagittal and conicity indexes. Women showed higher means for body mass index; arm, waist, thigh and hip circumferences; biceps, triceps, subscapular, suprailiac, pectoral, thigh, calf, and mean of six skinfolds; fat arm area, waist-to-height ratio and sagittal abdominal diameter-to-height ratio. The younger elderly presented higher measures of forearm, arm, muscle arm and thigh circumferences; and muscle arm area, in relation to the older. The robust elderly had higher measures of height, knee-height, muscle arm circumference and muscle arm area; and lower fat arm area, thigh, pectoral, biceps, triceps and calf skinfolds; and sagittal abdominal diameterto-height ratio, than the pre-frail and frail seniors. The frail elderly had lower calf and forearm circumferences than the robust elderly, and higher waist-to-height, waist-to-thigh and waist-to-calf ratios, and conicity and sagittal indexes. Conclusions: Anthropometric measures were associated with gender, age and frailty. In men, the mean measures of size, build and muscle mass reserve were higher. In women, the mean measures of fat reserve were higher and the association of the measures with age group was more frequent. Frailty proved to be associated with muscle mass loss. The frail elderly had lower measures of size and complexion.

Apolipoprotein E genetic polymorphism, serum lipoprotein levels and breast cancer risk: A case-control study.

The purpose of this study was to evaluate the association between apolipoprotein E (APOE) allelic frequency, serum lipoproteins and breast cancer (BC). We conducted a nested case-control study within a cohort including 47 cases and 165 controls. Polymerase chain reaction-restriction fragment length polymorphism analyses of the APOE polymorphism were performed. In general, participants with the genotype including alleles e2 and e3 tended to have lower serum triglycerides, total cholesterol and low-density lipoprotein cholesterol levels and higher high-density lipoprotein (HDL) cholesterol levels compared to participants homozygous for the e3 allele and participants heterozygous for the e3 and e4 alleles, respectively. BC patients exhibited higher mean levels of total serum cholesterol (P=0.070), dietary fat intake (P=0.020) and dietary cholesterol intake (P=0.017) compared to control subjects. The allelic distribution between the two groups revealed that the presence of the e2 allele was positively associated with the absence of BC, whereas the e4 allele was positively associated with the BC case group (P=0.019). The distribution of the APOE genotypes was not significantly different between cases and controls (P=0.172). The concomitant presence of the e2 and e4 alleles was positively associated with the absence of BC and e4/e4 homozygosity was positively associated with BC (P=0.021). Our findings suggested that APOE polymorphism plays an important role in the development of BC, particularly when associated with higher serum triglyceride levels.

Association of adipokines and adhesion molecules with indicators of obesity in women undergoing mammography screening.

BACKGROUND: The soluble cell adhesion molecules and adipokines are elevated in patients with obesity, hypertension, type 2 diabetes mellitus, breast cancer and atherosclerosis. OBJECTIVE: To investigate the relationship between anthropometric profile, dietary intake, lipid profile and fasting glycemia with serum levels of adipokines (adiponectin and PAI-1) and adhesion molecules (ICAM-1 and VCAM-1) in women without breast cancer undergoing routine mammographic screening. DESIGN: Transversal study. SUBJECTS: One hundred and forty-five women over 40-years old participated in this study. RESULTS: In 39.3% of cases the BMI was above 30 kg/m2; 46.9% had hypertension, 14.5% had type 2 Diabetes Mellitus, 31.7% had dyslipidemia and 88.3% presented a waist-to-hip ratio ≥ 0.8. A linear correlation was found between serum levels of PAI-1 and triglycerides, between serum levels of PAI-1 and WHR and between serum levels of VCAM-1 and BMI. CONCLUSION: We found a high prevalence of obesity and metabolic syndrome. PAI-1 and VCAM-1 levels were correlated with clinical indicators of obesity and overweight.

Aspectos éticos e nutricionais em uma amostra de idosos institucionalizados e não-institucionalizados / Ethical and nutrition issues in a sample of institutionalized and non-institutionalized elderly

O presente estudo avaliou o estado nutricional, a qualidade de vida e a capacidade de tomada de decisão em idosos no município de Porto Alegre, RS. O estudo envolveu amostras compostas por 73 idosos moradores de Instituições de Longa Permanência (ILPs) e por 175 idosos não institucionalizados. Os dados obtidos mostraram que os idosos institucionalizados, comparados aos não institucionalizados, apresentaram diferenças significativas no risco para desenvolver doenças relacionadas ao estado nutricional, na qualidade de vida total e em seus domínios (Habilidade Sensorial, Autonomia, Atividades do passado, presente e futuro, Participação Social, Morte e Morrer e Intimidade). A maioria dos idosos, sejam eles institucionalizados ou não, demonstrou capacidade para tomada de decisão.

This study assessed the nutritional status, quality of life and decision making capacity in elderly people in Porto Alegre,RS. The study involved samples composed of 73 elderly residents of long-stay institutions (ILPS) and 175 non-institutionalized elderly. The data showed that institutionalized elderly compared to non-institutionalized, significant differences in risk for developing diseases related to nutritional status, the overall quality of life and its domains (Sensory Skill, Autonomy, activities of the past, present and future Social Participation, Death and Dying and Intimacy). The majority of elderly persons studied, whether institutionalized or not, preserve decision making capacity.